The first phase of the menstrual cycle is the follicular or proliferative phase. It occurs from day one to day 14 of the menstrual cycle, based on the average duration of 28 days. The variability in the length of the menstrual cycle occurs due to variations in the length of the follicular phase. The main hormone during this phase is estrogen.. Menstrual cycle. The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone.The uterine cycle governs the preparation and maintenance of the lining of the.

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Up to two weeks before a menstrual period, hormone-driven changes in the body trigger a collection of premenstrual symptoms (PMS). These changes can cause cramps, breast pain, fatigue, mood swings, and upset stomach. Individual symptoms may vary since everyone's menstrual cycle is unique. Other body changes during the menstrual cycle are less.. The follicular phase of the menstrual cycle occurs when the antral follicle develops into a preovulatory follicle in preparation for ovulation. The follicular phase (ie, follicle development) begins on day one, which is characterized by the onset of menstruation and continues today 14 (ie, ovulation) of a typical 28-day cycle.